A diferencia del carcinoma colorrectal, no se recomienda el escrutinio de neoplasias del tubo digestivo alto para la población general. Sin embargo, existe evidencia sólida que avala que el cáncer del tubo digestivo superior puede desarrollarse en asociación con múltiples patologías subyacentes, conocidas como lesiones premalignas.
Dysregulation of innate immune response by Toll-Like Receptors (TLRs) is a key feature in Ulcerative Colitis (UC). Most studies have focused on TLR2, TLR3, and TLR4 participation in UC. However, few studies have explored other TLRs. Therefore, the aim of this study was to evaluate the mRNA profiles of TLR1 to 9 in colonic mucosa of UC patients, according to disease activity.
Multiple lymphomatous polyposis (MLP) is an uncommon type of primary non-Hodgkin gastrointestinal (GI) Bcell lymphoma characterized by the presence of multiple polyps along the GI tract. Malignant cells of MLP have mantle cell characteristics and thus are considered to be the counterpart of the mantle cell lymphoma (MCL) in the GI tract. Since 1961, no more than 70 well-documented cases have been published. We report the case of 53-yearold man diagnosed as having MLP.